Thermo Fisher Scientific TCAP Polyclonal Antibody
TCAP 단백질에 특이적인 Rabbit Polyclonal 항체로 Western Blot에 적합합니다. 인간 시료에 반응하며, 단백질 A로 정제된 액상 형태입니다. PBS(2% sucrose) 버퍼에 보관되며, -20°C에서 냉동 보관을 권장합니다. 근육 단백질 titin과 관련된 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human TCAP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2610361 |
Product Specific Information
- Peptide sequence: IQLQELLALE TALGGQCVDR QEVAEITKQL PPVVPVSKPG ALRRSLSRSM
- Sequence homology: Cow 100%, Dog 100%, Goat 100%, Guinea Pig 100%, Horse 100%, Human 100%, Mouse 100%, Rabbit 100%, Rat 100%
Target Information
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere and serves as a scaffold for myofibrils and other muscle-related proteins.
TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and acts as a substrate of titin kinase. These interactions are critical to sarcomere assembly.
Mutations in the TCAP gene are associated with limb-girdle muscular dystrophy type 2G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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