Thermo Fisher Scientific KPNA7 Polyclonal Antibody
Human KPNA7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot에 최적화되어 있으며, 0.5 mg/mL 농도의 액상 형태로 제공. PBS와 sucrose buffer에 보관하며, 핵 단백질 수송 연구에 적합.
- 판매단위
- pk
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Thermo Fisher Scientific KPNA7 Polyclonal Antibody
Applications
- Western Blot (WB): Tested at 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human KPNA7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690127 |
Product Specific Information
This target displays homology in the following species:
- Cow: 79%
- Dog: 93%
- Human: 100%
- Pig: 79%
- Yeast: 90%
Target Information
Karyopherin is a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits. It targets proteins with nuclear localization signals to the nuclear pore complex (NPC) via an energy-dependent, Ran-mediated mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit remains at the NPC.
KPNA7 is most closely related to KPNA2 but primarily localizes to the nucleus. It may play a role in transporting essential nuclear proteins required for early embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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