Thermo Fisher Scientific Phospho-RAD52 (Tyr104) Polyclonal Antibody
Phospho-RAD52 (Tyr104) 폴리클로날 항체로 Western blot 및 IHC(P) 분석에 적합. 인간 RAD52 인산화 부위 기반 합성 펩타이드 면역원 사용. 고농도(1 mg/mL) 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Phospho-RAD52 (Tyr104) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human RAD52 around the phosphorylation site of Tyr104 (K-F-YP-V-G) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555296 |
Target Information
DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. These breaks are generally repaired via two distinct mechanisms: homologous recombination (HR) or non-homologous end joining (NHEJ).
Homologous recombination requires the activity of the RAD52 epistasis group, including RAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2.
RAD52 catalyzes strand annealing reactions and can form oligomers that attach to ends of single-stranded DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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