Thermo Fisher Scientific Collagen IV Polyclonal Antibody
Rabbit polyclonal antibody targeting Collagen IV from human and bovine placenta. Verified for WB, IHC(P), ICC/IF, and IP. High specificity and affinity purified. Suitable for studies of basement membrane structure and related genetic disorders.
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Thermo Fisher Scientific Collagen IV Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | View 1 publication |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
| Immunoprecipitation (IP) | 1:100 | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Bovine, Human, Mammal, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Collagen Type IV from human and bovine placenta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.18 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1956972 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Collagen IV is a major structural protein of the basement membrane found in tissues such as kidneys, lungs, and skin. It forms a network-like scaffold that provides mechanical support and stability. Collagen IV consists of three alpha chains encoded by COL4A1, COL4A2, and COL4A3 genes. Mutations in these genes are associated with disorders such as Alport syndrome and Goodpasture syndrome, affecting renal and pulmonary function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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