Thermo Fisher Scientific MAGEB1 Monoclonal Antibody (OTI2B12)

Applications

Western Blot (WB)

• Assay-dependent

Immunohistochemistry (Paraffin) (IHC (P))

• Dilution: 1:100

Product Specifications

Target Information

This gene is a member of the MAGEB gene family. Members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50–68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that this gene family enables the same function to be expressed under different transcriptional controls.
This gene is localized in the DSS (dosage-sensitive sex reversal) critical region and is expressed in testis and in a significant fraction of tumors of various histological types. This gene and other MAGEB members are clustered on chromosome Xp22–p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene; however, the full-length nature of some variants has not been defined.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.