Thermo Fisher Scientific IKZF4 Polyclonal Antibody
Human IKZF4 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:20–1:50 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 버퍼에 보관. 단백질 발현 및 전사 억제 연구용.
- 카탈로그번호
- PA561861
- 판매단위
- pk
카탈로그
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Applications
Tested Applications and Dilutions
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IKZF4. Recombinant protein control fragment: Product #RP-91318 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642683 |
Product Specific Information
Immunogen sequence:
LQLQLYLPSC SLLQGSGDSS LEKEFLGAPV GPSVSTPNSQ HSSPSRSLSA NSIKVEMYSD EESSRLLGPD ERLLEKDDSV IVEDSLSEPL GYCDGSG
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 84%
Target Information
DNA-binding protein that binds to the 5′GGGAATRCC-3′ Ikaros-binding sequence.
Functions as a transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2.
May be involved in the development of central and peripheral nervous systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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