Thermo Fisher Scientific PLAC1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human PLAC1 protein. Validated for IHC with dilution 1:50–1:200. Unconjugated liquid form at 0.10 mg/mL. Suitable for cancer research and placental protein studies. For research use only.
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Applications
- Immunohistochemistry (IHC)
Tested dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PLAC1 (amino acids 22–84) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645620 |
Product Specific Information
Immunogen sequence:
GQSPMTVLCS IDWFMVTVHP FMLNNDVCVH FHELHLGLGC PPNHVQPHAY QFTYRVTECG IRA
Sequence identity:
- Mouse: 78%
- Rat: 76%
Target Information
PLAC1 (Placenta-specific protein 1) was initially identified as a protein expressed specifically in the placenta and trophoblast-derived cells during embryonic development. It is also ectopically expressed in various human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein thought to have a receptor-like function in modulating cell-cell or ligand-receptor interactions unique to the maternal-placental interface.
Decreased PLAC1 expression correlates with reduced cyclin D1 and AKT kinase expression, suggesting its potential as a target for immunotherapeutic cancer treatments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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