
Thermo Fisher Scientific K19/CYFRA21-1 Polyclonal Antibody
인간 K19/CYFRA21-1 항원을 인식하는 Rabbit Polyclonal Antibody로 다양한 면역학적 응용(WB, IHC, ICC, Flow, ELISA)에 적합합니다. Protein A로 정제된 액상 형태이며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human K19/CYFRA21-1, amino acids 301–400 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratin 19 is a member of the intermediate filament protein subfamily, characterized by biochemical diversity represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins have molecular weights ranging from 40–68 kDa and isoelectric points between 4.9–7.8.
Each epithelial tissue expresses specific cytokeratin patterns related to tissue type and differentiation stage. These expression patterns are valuable in distinguishing epithelial malignancies. Cytokeratin antibodies assist in tumor differential diagnosis via immunohistochemistry and are also useful in cytopathology and flow cytometry assays.
Cytokeratin 19 is not expressed in hepatocytes, making it useful for identifying liver metastases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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