Thermo Fisher Scientific LGI1 Recombinant Rabbit Monoclonal Antibody (JE54-88)
LGI1 단백질을 표적으로 하는 재조합 토끼 모노클로날 항체로 인간 및 생쥐 시료에 반응합니다. Western blot에 적합하며, 고순도의 Protein A 정제 항체입니다. 1 mg/mL 농도로 액상 형태이며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE54-88 |
| Immunogen | Recombinant protein within Human LGI1 aa 130–270 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2890397 |
Target Information
The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is part of a family of proteins containing leucine-rich repeats (LRRs), similar to transmembrane signaling molecules and receptors. It acts as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 are associated with autosomal dominant lateral temporal epilepsy (ADTLE), characterized by focal seizures with auditory symptoms. Two isoforms of LGI1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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