Thermo Fisher Scientific NALP2 Polyclonal Antibody
인간 NALP2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. Western blot에 적합하며, 액상 형태로 제공됩니다. 고순도 정제된 항체로 염증 및 세포사멸 관련 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-TEKHHPWAERPSSHD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933201 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:4,000.
Target Information
NALP2 belongs to a family of cytoplasmic proteins involved in cell responses to apoptotic and inflammatory stimuli. Unlike NALP1, NALP2 contains a NACHT domain, leucine-rich repeat (LRR), and pyrin-containing domain (PYD). It interacts with ASC, CARD8, and caspase-1 to form an inflammasome with high proIL-1β processing activity. NALP2 functions as a modulator of NF-κB and procaspase-1 activation in macrophages and may act as an innate pathogen sensor similar to toll-like receptors (TLRs). Two alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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