Thermo Fisher Scientific RXRG Polyclonal Antibody
RXRG 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간과 랫트 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. Affinity chromatography로 정제되어 높은 특이성과 재현성을 제공합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RXRG (Accession P48443), corresponding to amino acid residues D180–G230. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818645 |
Product Specific Information
This antibody detects endogenous levels of total RXR gamma.
Target Information
Retinoic Acid (RA), an active metabolite of vitamin A, plays a key role in the transition of proliferating precursor cells (e.g., carcinoma and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005).
The Retinoid X Receptor (RXR) family — including RXR alpha, beta, and gamma — preferentially binds 9-cis-RA and regulates gene transcription through heterodimerization with RA receptors.
RAs may play a therapeutic role in cervical cancer (Abu et al., 2005) and are important in neuronal development, with evidence suggesting retinoid signaling regulates synaptic plasticity, learning, and memory behaviors (Lane and Bailey, 2005).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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