Thermo Fisher Scientific UBXN2B Monoclonal Antibody (OTI1F9), TrueMAB
UBXN2B 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간 시료에 반응하며, 고순도의 액상 형태로 제공됩니다. ER 및 골지체 관련 단백질 연구에 유용한 연구용 항체입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F9 |
| Immunogen | Full length human recombinant protein of human UBXN2B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
UBXN2B (UBX domain-containing protein 2B), also known as NSFL1 cofactor p37 and p97 cofactor p37, is a 331 amino acid protein that contains one UBX domain and one SEP domain.
UBXN2B is required for ER and Golgi biogenesis and plays a role in their maintenance during interphase, as well as their reassembly at the end of mitosis.
Through interaction with VCP, UBXN2B forms a complex that has membrane fusion activity. This activity requires USO1-GOLGA2 tethering and BET1L, and also involves VCPIP1 (though not its deubiquitinating activity).
UBXN2B functions as an adapter protein essential for Golgi and endoplasmic reticulum biogenesis and maintenance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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