
Thermo Fisher Scientific Pembrolizumab Humanized Recombinant Human Monoclonal Antibody
인간 PD-1을 표적으로 하는 휴먼화 재조합 단일클론 항체로, 면역세포 활성화 연구에 적합. ELISA 등 다양한 면역실험에 사용 가능. 고순도 Protein A 정제, 낮은 엔도톡신 수준. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Pembrolizumab Humanized Recombinant Human Monoclonal Antibody
Applications
- ELISA
Tested Dilution
- 1:5,000–1:10,000
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Human / IgG4, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human PDCD1 / PD1 / CD279 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.3 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911151 |
Product Specific Information
- Endotoxin level < 0.01 EU/µg (LAL method)
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week.
- Store at -20 to -80°C for twelve months from the date of receipt.
Target Information
Pembrolizumab (Keytruda) is a humanized monoclonal antibody approved by the U.S. FDA for treatment of unresectable or metastatic melanoma.
It binds to the human PD-1 receptor (Programmed Cell Death Protein 1) and blocks interaction with PD-L1, resulting in activation of T-cell-mediated immune responses against tumor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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