Thermo Fisher Scientific CTHRC1 Polyclonal Antibody
Human CTHRC1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CTHRC1. Recombinant protein control fragment (Product #RP-93876). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640226 |
Product Specific Information
Immunogen sequence:
AIIYLDQGSP EMNSTINIHR TSSVEGLCEG IGAGLVDVAI WVGTCSDYPK GDASTGWNSV SRI
Sequence identity:
- Mouse: 98%
- Rat: 98%
Target Information
The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein transiently expressed in the arterial wall in response to injury. It contributes to vascular remodeling by inhibiting collagen expression and promoting cell migration.
CTHRC1 is highly expressed in multiple human cancers, including pancreatic cancer, where it influences tumor progression and metastasis. It also serves as an independent prognostic marker in gastric cancer. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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