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Thermo Fisher Scientific Pr3 Polyclonal Antibody
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Human Pr3 단백질을 인식하는 Rabbit IgG 폴리클로날 항체로, WB, IHC, Flow Cytometry에 사용 가능. 합성 펩타이드 면역원 기반으로 제작되었으며, PBS 버퍼에 동결건조 형태로 제공. 연구용으로만 사용.
- 판매단위
- pk
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마지막 업데이트 2025. 07. 29. 오전 05:23
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Thermo Fisher Scientific OSP00053G-500UG Pr3 Polyclonal Antibody 500 ug pk판매 단위 pk ·
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723,400원VAT 포함 795,740원
Thermo Fisher Scientific · Thermo Fisher Scientific Pr3 Polyclonal Antibody
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Flow Cytometry (Flow) | 10–50 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal region of human Pr3 (Leukocyte proteinase 3, AGP7, Myeloblastin, Wegener autoantigen) conjugated to an immunogenic carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: Pr3.
Target Information
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro).
By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration.
May play a role in neutrophil transendothelial migration, probably when associated with CD177. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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