Thermo Fisher Scientific KRTCAP2 Polyclonal Antibody
Thermo Fisher Scientific의 KRTCAP2 Polyclonal Antibody는 인간 KRTCAP2 단백질의 C-말단 합성 펩타이드에 대해 제작된 토끼 IgG 항체입니다. Western blot에 적합하며, 액상 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제, -20°C 보관 권장, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human KRTCAP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2689671 |
Product Specific Information
This target displays homology in the following species:
Cow: 93%
Dog: 93%
Guinea Pig: 79%
Horse: 93%
Human: 100%
Mouse: 86%
Pig: 93%
Rabbit: 93%
Rat: 100%
Target Information
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.
N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).
All subunits are required for maximal enzyme activity (PubMed:22467853).
May be involved in N-glycosylation of APP (amyloid-beta precursor protein).
Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1 (PubMed:21768116).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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