Thermo Fisher Scientific LILRB1/ILT-2/CD85j Monoclonal Antibody (VMP55)
LILRB1/ILT-2/CD85j 단일클론 항체(VMP55)는 인간, 마우스, 랫트에 반응하며 WB, ICC/IF, Flow, IP에 적합합니다. Protein A/G로 정제된 비결합 항체로, 4°C에서 보관합니다. 면역세포의 MHC class I 인식 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Immunoprecipitation (IP) | 1–2 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VMP55 |
| Immunogen | Hairy cell leukemia cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The LILRB1 gene belongs to the leukocyte immunoglobulin-like receptor (LIR) family located at chromosome region 19q13.4. The encoded protein is a subfamily B class receptor containing extracellular immunoglobulin domains, a transmembrane region, and cytoplasmic ITIM motifs. It is expressed on immune cells and binds to MHC class I molecules on antigen-presenting cells, transmitting inhibitory signals that regulate immune activation. This receptor helps control inflammatory responses and cytotoxicity to maintain immune balance and prevent autoreactivity. Multiple transcript variants encoding different isoforms exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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