Thermo Fisher Scientific RPS4Y1 Polyclonal Antibody

Applications

• Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50

Product Specifications

Product Specific Information

Immunogen sequence:
KVRKITVGVK GIPHLVTHDA RTIRYPDPVI KVNDTVQIDL GTGKIINFIK FDTGNLCMVI GGANLGRVGV ITNRERHPGS FDVVHVKDAN GNSFATRLSN IFVIGNGNKP WISLPRGKGI RLTVA

Highest antigen sequence identity to the following orthologs:

• Mouse: 91%
• Rat: 91%

Target Information

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.
This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, X-linked (RPS4X).
The 2 isoforms encoded by these genes are not identical but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial.
As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.