Thermo Fisher Scientific TRAF3IP1 Polyclonal Antibody
Human 및 비인간 영장류 반응성의 TRAF3IP1 폴리클로날 항체로, Rabbit IgG 기반. IHC(P) 실험에 5 µg/mL 농도로 사용 가능. Protein A로 정제된 액상형 항체로 PBS/BSA buffer에 보존. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A portion of amino acids 390–440 from human TRAF3IP1 was used as the immunogen for this antibody. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718846 |
Target Information
Tumor necrosis factor receptor (TNFR) superfamily members transmit signals regulating proliferation, differentiation, and apoptosis in various cell types. TNFR-associated factors (TRAFs) are a family of proteins that act as downstream signal transducers of the TNFR superfamily. TRAF3 contains an N-terminal ring finger/zinc finger region essential for downstream signaling.
MIP-T3 is associated with TRAF3, binding to taxol-stabilized microtubules and tubulin in vitro. When both proteins are overexpressed, MIP-T3 recruits TRAF3 to microtubules. The MIP-T3/TRAF3 interaction requires the coiled-coil TRAF-N domain of TRAF3, suggesting a novel mechanism for sequestering TRAF3 to the cytoskeletal network.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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