Thermo Fisher Scientific alpha Synuclein VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1198)
Recombinant alpaca VHH monoclonal antibody targeting human alpha-synuclein. Compatible with direct ELISA assays. High purity via metal-chelate chromatography. Supplied as liquid form in PBS without preservative. Suitable for Parkinson’s and Alzheimer’s...
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Thermo Fisher Scientific alpha Synuclein VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1198)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1198 |
| Immunogen | Recombinant Human SNCA / Alpha-synuclein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking. Alpha- and beta-synuclein selectively inhibit phospholipase D2, suggesting involvement in signaling pathways.
Defects in the SNCA gene, encoding alpha-synuclein, are implicated in the pathogenesis of Parkinson’s disease. Alpha-synuclein peptides are also major components of amyloid plaques in Alzheimer’s disease. Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant, and Dementia, Lewy Body.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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