Thermo Fisher Scientific ZGPAT Polyclonal Antibody
Thermo Fisher Scientific의 ZGPAT Polyclonal Antibody는 인간 ZGPAT 단백질의 N-말단 합성 펩타이드에 특이적인 항체로, WB 및 IHC에 적합합니다. Rabbit IgG 기반의 비결합형 액상 항체이며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA569192
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1.0 µg/mL |
| Immunohistochemistry (IHC) | 1:100 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human ZGPAT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688579 |
Product Specific Information
This target displays homology in the following species:
Cow: 93%
Dog: 85%
Guinea Pig: 93%
Human: 100%
Mouse: 100%
Rat: 100%
Sheep: 93%
Target Information
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggests it may act as a tumor suppressor. Able to suppress breast carcinogenesis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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