Thermo Fisher Scientific ZGPAT Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1.0 µg/mL

-

Immunohistochemistry (IHC)

1:100

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-Dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

synthetic peptide directed towards the N terminal region of human ZGPAT if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZGPAT,uniProtId:Q8N5A5-1,ncbiNodeId:9606,antigenRange:1,antigenLength:531,antigenImageFileName:PA5-69192_ZGPAT_Q8N5A5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-69192_ZGPAT_Q8N5A5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2688579

Product Specific Information

This target displays homology in the following species: Cow: 93%; Dog: 85%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Rat: 100%; Sheep: 93%

Target Information

Transcription repressor that specifically binds the 5-GGAG\[GA\]A\[GA\]A-3 consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.