Thermo Fisher Scientific Phospho-APC6 (Thr580) Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Store vial at -20°C prior to opening.
• Aliquot contents and freeze at -20°C or below for extended storage.
• Avoid cycles of freezing and thawing.
• Centrifuge product if not completely clear after standing at room temperature.
• Stable for several weeks at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.

This antibody is specific for phosphorylated human APC6 protein at the pT580 residue.
BLAST analysis indicates 100% homology of the immunizing sequence with APC6 from human.
No cross-reactivity is expected with homologues from other sources.
This antibody is expected to react with all isoforms of this protein, with minimal reactivity to the non-phosphorylated form.

Target Information

The protein encoded by this gene is structurally similar to the CDC46 protein from S. cerevisiae, which is involved in the initiation of DNA replication.
It belongs to the MCM family of chromatin-binding proteins and interacts with other family members.
The encoded protein is upregulated during the transition from G0 to G1/S phase of the cell cycle and may play a role in cell cycle regulation.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.