Thermo Fisher Scientific TRPV2 Polyclonal Antibody
TRPV2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(F), IP 등 다양한 응용에 사용 가능. 동결건조 형태로 제공되며, 재구성 후 -20°C에서 보관. 비캡사이신성 고온 활성화 이온 채널 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent | - |
| Immunoprecipitation (IP) | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)KKNPTSKPGKNSASEE, corresponding to amino acid residues 735–750 of rat TRPV2 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.65 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736748 |
Product Specific Information
This product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: Add 50 µL of deionized water.
Target Information
VRL-1 (also known as TRPV2) is a calcium-permeable, non-selective cation channel with outward rectification. It is regulated in part by growth factors such as IGF1, PDGF, and morphogenetic neuropeptides. Unlike other TRP channels, VRL-1 does not respond to capsaicin, acid, or moderate heat but is activated by high temperatures (threshold ~52°C).
Within sensory ganglia, VRL-1 is expressed in medium- to large-diameter neurons, suggesting a role in high-threshold heat response. It is also expressed beyond the sensory nervous system, implying activation by additional stimuli. VRL-1 is one of six members of the vanilloid-like TRP channel family, now classified as the TRPV family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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