Thermo Fisher Scientific ANAPC10 Polyclonal Antibody, MaxPab
Rabbit polyclonal antibody targeting human ANAPC10 protein. Validated for Western blot (1–5 µg/mL). Affinity-purified, unconjugated, liquid form in PBS buffer. Suitable for research on cell cycle regulation and mitosis-related APC/C complex functions.
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Applications
- Western Blot (WB): Tested dilution 1–5 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | ANAPC10 (AAH05217.1, 1–185 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MTTPNKTPPG ADPKQLERTG TVREIGSQAV WSLSSCKPGF GVDQLRDDNL ETYWQSDGSQ PHLVNIQFRR KTTVKTLCIY ADYKSDESYT PSKISVRVGN NFHNLQEIRQ LELVEPSGWI HVPLTDNHKK PTRTFMIQIA VLANHQNGRD THMRQIKIYT PVEESSIGKF PRCTTIDFMM YRSIR
Target Information
Cell cycle regulated protein ubiquitination and degradation within subcellular domains is essential for normal mitosis progression.
APC10 is a conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase controlling progression through mitosis and G1 phase.
APC/C degrades anaphase inhibitors, mitotic cyclins, and spindle-associated proteins, ensuring proper sequence of mitotic events.
APC10 may regulate substrate binding to the APC/C complex, similar to coactivators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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