Thermo Fisher Scientific Human PKN1 (PRK1), GST Tag Recombinant Protein
인간 PKN1(PRK1) 단백질을 Insect cell에서 발현한 GST-tag 재조합 단백질. Rho GTPase 의존성 신호전달 연구에 적합하며, 활성화된 단백질 키나아제 C 슈퍼패밀리 구성원. 고순도 정제, -80°C 보관, 연구용 전용.
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Thermo Fisher Scientific Human PKN1 (PRK1), GST Tag Recombinant Protein
Applications
- Kinase Assay (KA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Insect cells |
| Amino Acid Sequence | Full length |
| Tag | GST-tag |
| Molecular Weight | 132.1 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris, pH 7.5, with 0.02% Triton X-100, 50% glycerol, 2 mM DTT, 150 mM NaCl, 0.5 mM EDTA |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
For maximum recovery, please spin prior to use.
Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use original packaging until exhausted.
For larger sizes, aliquoting can reduce freeze/thaw cycles; aliquots below 20 µL are not recommended.
Never store kinase diluted.
If stored properly at -80°C, product is guaranteed for 6 months from date of purchase.
Protein Form: Full Length
Target Information
PKN1 (PRK1) belongs to the protein kinase C superfamily. It is activated by Rho family small G proteins and may mediate Rho-dependent signaling pathways. This kinase can also be activated by phospholipids. PDPK1/PDK1 is reported to phosphorylate this kinase, mediating insulin signals to the actin cytoskeleton.
Proteolytic activation by caspase-3 or related proteases during apoptosis suggests its involvement in apoptotic signal transduction.
Alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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