Thermo Fisher Scientific NGAL Monoclonal Antibody (15)
Rat NGAL 단백질을 인식하는 Mouse IgG1 단클론 항체로 ELISA 등 면역분석에 적합. 인간, 돼지, 개, 마우스 NGAL과 교차반응 없음. 단백질 A/G로 정제되었으며 PBS buffer에 보관. 연구용으로만 사용 가능.
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Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 15 |
| Immunogen | Recombinant rat NGAL precursor with C-terminal His-tag coupled to carrier |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.08 mg/mL (lot-dependent, may vary from 0.85–1.15 mg/mL) |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536219 |
Product Specific Information
ABS 039-15-02 shows no cross-reaction with human, pig, dog, or mouse NGAL.
Reactivity: ABS 039-15-02 binds free rat NGAL in solution.
Can be used as a capture antibody in a sandwich ELISA using biotinylated detection antibody ABS 039-32-02.
Rat NGAL measures 4–400 pg/mL in an optimized assay.
Target Information
NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin, and neutrophil lipocalin) is a 25 kDa glycosylated single-chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules.
NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B).
Low-level expression of NGAL in various epithelia may be increased in inflammation or cancers.
Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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