Thermo Fisher Scientific VN1B4, VN1B2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:2,000

-

Immunohistochemistry (IHC)

1:300-1:2,000

-

Miscellaneous PubMed (Misc)

-

View 2 publications 2 publications

Product Specifications

Species Reactivity

Mouse

Published species

Not Applicable

Host/Isotype

Rabbit / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from mouse vomeronasal type-1 receptor B4 (VN1B4, V1ra10, V1rb11) and vomeronasal type-1 receptor B2 (VN1B2, V1rb2, VRi2) conjugated to an immunogenic carrier protein was used as the antigen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: VN1B24 and also VN1B2 (see the Immunogen).

Target Information

Putative pheromone receptor implicated in the regulation of social and reproductive behavior. Expressed in a subset of sensory neurons located in the apical layer of the vomeronasal organ. Mice lacking V1RB2 show a disrupted pattern of axonal projections to the accessory olfactory bulb. Mice lacking all but one V1RA and V1RB gene (12% of the V1R repertoire) show a lack of chemosensory response to a subset of known pheromonal ligands and changes in maternal aggression as well as male reproductive behavior.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.