Thermo Fisher Scientific NME1 Monoclonal Antibody (UMAB91), UltraMAB
NME1 단백질을 표적으로 하는 UMAB91 클론의 마우스 모노클로날 항체. Western Blot, IHC, ICC/IF, ChIP 등 다양한 실험에 사용 가능. 고순도 친화 크로마토그래피 정제 및 무보존제 PBS 버퍼 제공. 연구용으로만 사용.
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Thermo Fisher Scientific NME1 Monoclonal Antibody (UMAB91), UltraMAB
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ChIP assay (ChIP) | Assay-dependent |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB91 |
| Immunogen | Full length human recombinant NME1 protein produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
NME1 was identified due to reduced mRNA transcript levels in highly metastatic cells.
Nucleoside diphosphate kinase (NDK) forms a hexamer composed of A (encoded by NME1) and B (encoded by NME2) isoforms.
Mutations in NME1 are associated with aggressive neuroblastomas.
Two transcript variants encoding different isoforms have been found.
Co-transcription with NME2 generates NME1-NME2 fusion transcripts encoding a protein sharing identity with both gene products.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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