Thermo Fisher Scientific MRP1 Polyclonal Antibody
MRP1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, ELISA, IP 등 다양한 응용에 사용 가능. Rat MRP1 특이적 합성 펩타이드로 면역화된 Rabbit IgG 항체이며, 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to unique amino acid sequences on rat multidrug resistance-associated protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across cellular membranes and are divided into seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This transporter belongs to the MRP subfamily involved in multidrug resistance. It functions as a multispecific organic anion transporter with substrates including oxidized glutathione, cysteinyl leukotrienes, and activated aflatoxin B1.
Additionally, it transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion produces several splice variants, all maintaining the original open reading frame.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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