Thermo Fisher Scientific TRIM5 alpha Polyclonal Antibody
TRIM5 alpha 단백질을 인식하는 Polyclonal 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. Human 시료에 반응하며, Goat에서 생산된 IgG 타입입니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3–6 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (CNIEKNENYQPK) corresponding to internal amino acids of TRIM5 (aa 385–397) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10978833 |
Product Specific Information
This antibody is predicted to react with human based on sequence homology.
It has been tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
The protein encoded by this gene is a member of the tripartite motif family. The TRIM motif includes three zinc-binding domains—a RING, a B-box type 1, and a B-box type 2—and a coiled-coil region. The protein forms homo-oligomers via the coiled-coil region and localizes to cytoplasmic bodies. It functions as an E3 ubiquitin-ligase and ubiquitinates itself to regulate subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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