Thermo Fisher Scientific Kir4.1 (KCNJ10) Polyclonal Antibody
Kir4.1(KCNJ10) 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 시료에 반응합니다. IHC(P)에서 1:1,000–1:2,500 희석 비율로 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 신경계 및 뇌 조직 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KCNJ10 (amino acids 310–379). Recombinant protein control fragment: Product #RP-108298 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792206 |
Product Specific Information
Immunogen sequence:
EFTPAISLSA SGKYIADFSL FDQVVKVASP SGLRDSTVRY GDPEKLKLEE SLREQAEKEG SALSVRISNV
Target Information
The KIR (inwardly rectifying potassium channel) family allows greater potassium influx into cells than efflux.
KIR4.1 (also known as Kir1.2) is highly expressed in the brain, including glial cells, astrocytes, and cortical neurons.
It is also found in myelin-synthesizing oligodendrocytes and plays a crucial role in myelination during nervous system development.
The human KIR4.1 gene maps to chromosome 1.
KIR4.2 (Kir1.3) is expressed in kidney, lung, heart, thymus, and thyroid during development and maps to chromosome 21, potentially linked to Down syndrome pathogenesis.
KIR5.1 forms functional channels only by coexpression with KIR4.1 or KIR4.2 in kidney and pancreas.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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