Thermo Fisher Scientific ABC2 Polyclonal Antibody
Rabbit polyclonal antibody recognizing ABC2 protein. Validated for IHC and IP applications. Supplied as a liquid, unconjugated form at 1 mg/mL concentration. Recommended storage at 4°C and shipping on wet ice. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between residues 250 and 300 of target protein (C17orf71, UniProt ID: Q8ND04-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
Target Information
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex). In the SMG1C complex, it mediates recruitment of SMG1 to the ribosome:SURF complex and suppresses SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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