Thermo Fisher Scientific FAM111A Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FAM111A. Recombinant protein control fragment (Product #RP-97447). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FAM111A,uniProtId:Q96PZ2-1,ncbiNodeId:9606,antigenRange:252-356,antigenLength:611,antigenImageFileName:PA5-59091_FAM111A_Q96PZ2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-59091_FAM111A_Q96PZ2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641222

Product Specific Information

Immunogen sequence: STQPVDELEG RYFQVEVEKR MVPSAAASQN PESEKRNTCV LREQIVAQYP SLKRESEKII ENFKKKMKVK NGETLFELHR TTFGKVTKNS SSIKVVKLLV RLSDS

Highest antigen sequence identity to the following orthologs: Mouse - 48%, Rat - 44%.

Target Information

With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and isconsidered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene isimportant for regulation ofcellcycle arrest and apoptosisfollowing double strand DNA breaks. Atmmutation leadsto the disorderknown as ataxia telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms` tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitzsyndrome are also associatedwith defectsin chromosome 11. The FAM111A gene product has been provisionally designated FAM111A pending furthercharacterization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.