Thermo Fisher Scientific RBM28 Polyclonal Antibody
Thermo Fisher Scientific의 RBM28 폴리클로날 항체는 인간 유래 단백질을 인식하며 Western blot 및 IHC(P) 분석에 적합합니다. 합성 펩타이드 면역원으로 제조되어 높은 특이성과 재현성을 제공합니다. 액상 형태로 0.5 mg/mL 농도이며 -20°C에서 안정적으로 보관 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4–8 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human RBM28 (aa 651–700) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2576963 |
Product Specific Information
- Peptide sequence: QTKAEVEQVE LPDGKKRRKV LALPSHRGPK IRLRDKGKVK PVHPKKPKPQ
- Sequence homology:
Cow: 93%
Dog: 100%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 85%
Target Information
Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes. Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, linking these intracellular compartments. The ORP3-VAPA complex stimulates RRAS signaling which attenuates integrin beta-1 (ITGB1) activation at the cell surface. With VAPA, may regulate ER morphology. Plays a role in regulation of the actin cytoskeleton, cell polarity, and cell adhesion. Binds phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3. Also binds 25-hydroxycholesterol and cholesterol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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