Thermo Fisher Scientific Pannexin 1 Polyclonal Antibody, FITC
FITC 형광 표지된 Pannexin 1 폴리클로날 항체로 인간 단백질에 반응합니다. Western blot, ELISA, IP에 사용 가능하며 높은 특이성과 감도를 제공합니다. 연구용으로 ER Ca2+ 조절 및 세포 간 ATP 통로 연구에 적합합니다.
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- pk
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Thermo Fisher Scientific Pannexin 1 Polyclonal Antibody, FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region from human Pannexin 1 protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The pannexin gene family encodes a second class of putative gap junction proteins and is highly conserved among invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels.
Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 forms a mechanosensitive ATP-permeable channel between adjacent cells and within the endoplasmic reticulum. It may function as a Ca²⁺-leak channel regulating ER Ca²⁺ homeostasis and neural stem/progenitor cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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