Thermo Fisher Scientific SERPINC1 Polyclonal Antibody
Human SERPINC1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며, 고순도(>95%) 항원 친화 크로마토그래피로 정제됨. 혈액 응고 관련 연구용으로 사용 가능. 연구용 한정 제품.
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Thermo Fisher Scientific SERPINC1 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in Human SERPINC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803602 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
The protein encoded by the SERPINC1 gene is a plasma protease inhibitor and a member of the serpin superfamily. It inhibits thrombin and other activated serine proteases of the coagulation system, regulating the blood coagulation cascade.
The protein includes two functional domains:
- Heparin binding domain at the N-terminus
- Reactive site domain at the C-terminus
The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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