Thermo Fisher Scientific LRBA Polyclonal Antibody
Human LRBA 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF 실험에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용하며 장기 보관 시 -20°C에서 보관 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LRBA. Recombinant protein control fragment (Product #RP-92444) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643453 |
Product Specific Information
Immunogen sequence:
SVLMVSKYRD ILEPQNERHS QSCTETGSEN ENVSLSEITP AAFSTLTTAS VEESESTSSA RRRDSGIGEE TATGLGSHVE VTPHTAPPGV SAGPDAISEV LSTLSLEVNK SPETKNDRGN DLDTKATPSV SV
- Highest antigen sequence identity to the following orthologs:
- Mouse: 72%
- Rat: 73%
Target Information
The LRBA gene encodes a protein belonging to the WDL-BEACH-WD (WBW) family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The protein associates with protein kinase A and may participate in directing intracellular vesicles to activated receptor complexes, aiding secretion or membrane deposition of immune effector molecules. Mutations in LRBA are linked to common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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