Thermo Fisher Scientific SHIP1 Recombinant Rabbit Monoclonal Antibody (9G11)
SHIP1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, IP에 적합합니다. 높은 특이성과 재현성을 제공하며 인간 시료에 반응합니다. HEK293 세포에서 발현된 항체로 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:5,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunoprecipitation (IP)
- Tested Dilution: 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 9G11 |
| Immunogen | A synthesized peptide derived from human SHIP1 (UniProt ID: Q92835-1, antigen range: 1106–1121) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.79 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898207 |
Product Specific Information
This antibody has been tested in direct ELISA.
Target Information
This gene belongs to the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression is restricted to hematopoietic cells, where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5′ phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, affecting multiple signaling pathways. Overall, it functions as a negative regulator of myeloid cell proliferation and survival. Alternate transcriptional splice variants encoding different isoforms have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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