Thermo Fisher Scientific Actin-like 7A Polyclonal Antibody
Actin-like 7A 단백질을 인식하는 Rabbit Polyclonal 항체로, Human과 Mouse 시료에 반응합니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반의 안정화 버퍼에 보관되며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–327 of Human ACTL7A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548778 |
Product Specific Information
- Recommended positive controls: NIH-3T3
- Predicted reactivity: Mouse (84%), Rat (85%), Chimpanzee (99%), Bovine (87%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The ACTL7A gene encodes a member of the actin-related protein (ARP) family, sharing significant sequence identity with conventional actins. Both actins and ARPs possess an actin fold, an ATP-binding cleft common to these proteins. ARPs are involved in various cellular processes including vesicular transport, spindle orientation, nuclear migration, and chromatin remodeling.
ACTL7A and its related gene ACTL7B are intronless and located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on chromosome 9q31. Although expressed in many adult tissues, ACTL7A’s precise function remains unclear, and it is not believed to contribute to dysautonomia pathogenesis.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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