Thermo Fisher Scientific PFKFB1 Polyclonal Antibody
Human PFKFB1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 0.67 mg/mL 농도. 다양한 종에 예측 반응성 보유, 연구용으로 적합.
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Thermo Fisher Scientific PFKFB1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–194 of Human PFKFB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.67 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546839 |
Product Specific Information
- Recommended positive controls: 293T, H1299, HeLa, Molt-4, Raji
- Predicted reactivity: Mouse (93%), Rat (94%), Pig (98%), Bovine (96%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein. This mechanism mediates most signal transduction in eukaryotic cells, regulating metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
With more than 500 gene products, the protein kinase family is one of the largest in eukaryotes. The family is classified into eight major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group includes 63 kinases such as:
- Cyclic nucleotide-regulated protein kinases (PKA & PKG)
- Diacylglycerol-activated/phospholipid-dependent protein kinases (PKC)
- RAC/Akt protein kinases
- Kinases phosphorylating G protein-coupled receptors (ARK)
- Kinases phosphorylating ribosomal protein S6 (RSK)
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-29363_PFKFB1_P16118-1_Rabbit.svg, PA5-29363_PFKFB1_P16118-1_Rabbit_PDP.jpeg)
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