Thermo Fisher Scientific Phospho-C/EBP alpha (Thr230) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

Product Specifications

Target Information

The C/EBP (CCAAT/enhancer binding protein) family of transcription factors—alpha, beta, delta, and epsilon—are widely expressed proteins found in a variety of tissues. These domains contain an evolutionarily conserved five-amino acid motif (regulatory domain motif, RDM) that conforms to the consensus sequence (I/V/L)KXEP.
One of the major roles of these transcription factors is metabolic regulation in liver and fat cells. Studies suggest that these transcription factors act in a cascade aiding in adipose cell development.
Three C/EBP beta isoforms (LAP*, LAP, and LIP) arise from different translation initiation and display distinct functions in gene regulation.
From a neurological standpoint, C/EBPs have been implicated in nerve growth factor mediation, synaptic plasticity alteration, and inflammatory response in Alzheimer’s disease patients.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.