Thermo Fisher Scientific Alcohol Dehydrogenase 1A Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
NYCLKNDVSN PQGTLQDGTS RFTCRRKPIH HFLGISTFSQ YTVVDENAVA

• Short-term storage: 2–8°C up to 1 week
• Long-term storage: -20°C in small aliquots to prevent freeze-thaw cycles
• Predicted homology:
  • Cow: 86%
  • Dog: 100%
  • Guinea Pig: 92%
  • Horse: 93%
  • Human: 100%
  • Rabbit: 92%
  • Rat: 92%
  • Yeast: 85%
  • Zebrafish: 79%

Target Information

This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta, and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. It is found in a cluster with six additional alcohol dehydrogenase genes on chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.