Thermo Fisher Scientific AMT Polyclonal Antibody
Thermo Fisher Scientific의 AMT Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 Rabbit IgG 항체입니다. Western blot, ICC/IF, ELISA에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. -20°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 107–386 of human AMT (NP_001158184.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.72 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854796 |
Product Specific Information
Immunogen sequence:
AELRPNQGTL SLFTNEAGGI LDDLIVTNTS EGHLYVVSNA GCWEKDLALM QDKVRELQNQ GRDVGLEVLD NALLALQGPT AAQVLQAGVA DDLRKLPFMT SAVMEVFGVS GCRVTRCGYT GEDGVEISVP VAGAVHLATA ILKNPEVKLA GLAARDSLRL EAGLCLYGND IDEHTTPVEG SLSWTLGKRR RAAMDFPGAK VIVPQLKGRV QRRRVGLMCE GAPMRAHSPI LNMEGTKIGT VTSGCPSPSL KKNVAMGYVP CEYSRPGTML LVELPSGPCF
Target Information
The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of four protein components:
- P protein: Pyridoxal phosphate-dependent glycine decarboxylase
- H protein: Lipoic acid-containing protein
- T protein: Tetrahydrofolate-requiring enzyme
- L protein: Lipoamide dehydrogenase
Glycine encephalopathy (GCE) may be due to a defect in any one of these enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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