Thermo Fisher Scientific OATP1 Polyclonal Antibody
Human OATP1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot 및 Immunocytochemistry에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공. 연구용으로만 사용 가능하며, 장기 보관 시 -20°C에서 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human OATP1 (Recombinant protein control fragment, Product #RP-105520) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2662878 |
Product Specific Information
- Immunogen sequence:
FLPNTLPKEGL ETNADIIKNE NEDKQKEEVK KEKYGITKDF LPFMKSLSCN - Highest antigen sequence identity to orthologs:
- Mouse: 65%
- Rat: 63%
Target Information
The organic anion transporting polypeptides, OATP-A (also designated OATP1, OATP1A2, and SLC21A3) and OATP-C (also designated OATP2, SLC21A6, and LST1), mediate hepatic uptake of cardiac glycosides.
OATP-C expression is inducible by phenobarbital and pregnenolone-16a-carbonitrile, increasing the liver's ability to extract cardiac glycosides from plasma.
OATP-A is expressed in liver and kidney and mediates sodium-independent uptake of anionic steroid conjugates such as dehydroepiandrosterone sulfate, estradiol-17-glucuronide, and prostaglandin.
OATP-C is exclusively expressed in liver and localized to the basolateral hepatocyte membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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