Thermo Fisher Scientific RXRA Polyclonal Antibody
Human 및 Rat에 반응하는 RXRA 폴리클로날 항체로 Western blot과 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제된 고순도 항체. PBS 기반 완충액에 보관되며 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:10,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Retinoid X Receptor alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.98 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792537 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (99%), Rat (99%), Bovine (97%).
- Positive Control: HepG2, rat liver.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Retinoic Acid (RA), the active metabolite of vitamin A, regulates the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells.
The Retinoid X Receptors (RXRs) family — RXR alpha, beta, and gamma — preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors.
RAs may play a therapeutic role in cervical cancer and are known to be involved in neuronal development. Increasing evidence indicates that retinoid signaling regulates synaptic plasticity and associated learning and memory behaviors.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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