Thermo Fisher Scientific HOXB5 Polyclonal Antibody

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
ASSSHFGAVG ESSRAFPAPA QEPRFRQAAS SCSLSSPESL PCTNGDSHGA KPSASSPSDQ ATSASSSANF TEIDEASASS EPEEAASQLS SPSLARAQPE PMATSTAAPE GQTPQIFPWM R

Target Information

The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis.
Hox proteins are involved in controlling axial patterning, leukemias, and hereditary malformations.
HoxB5 (homeobox protein Hox-B5), also known as HOX2, HU-1, HOX2A, Hox2.1, or HHO.C10, is a member of the Antp homeobox (Hox) family. It is a 269 amino acid long nuclear protein expressed in the central nervous system.
HoxB5 contains one homeobox DNA-binding domain and plays a role in the regulation of lung and gut development, providing cells with positional identities on the anterior-posterior body axis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.