Thermo Fisher Scientific Burosumab Recombinant Human Monoclonal Antibody

Applications

• ELISA (ELISA): Assay-dependent

Product Specifications

Product Specific Information

• Endotoxin level: < 0.01 EU/µg (LAL method)
• Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
• Store at 2–8°C for one week.
• Store at -20 to -80°C for up to twelve months from the date of receipt.

Target Information

Burosumab is a biosimilar antibody that targets FGF23.
FGF23 encodes a member of the fibroblast growth factor family, which regulates phosphate metabolism and plays roles in:

• Embryonic development
• Cell growth and morphogenesis
• Tissue repair
• Tumor growth and invasion

Mutations in FGF23 are associated with:

• Autosomal dominant hypophosphatemic rickets
• Oncogenic hypophosphatemic osteomalacia
• Familial tumoral calcinosis with hyperphosphatemia

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.