Thermo Fisher Scientific FBXW5 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

FBXW5 (AAH00850.1, 1 a.a. approximately 159 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FBXW5,uniProtId:Q969U6-1,ncbiNodeId:9606,antigenRange:1-566,antigenLength:566,antigenImageFileName:H00054461-B01P_FBXW5_Q969U6-1_House_mouse.svg,antigenImageFileNamePDP:H00054461-B01P_FBXW5_Q969U6-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MGLSPDNRYL YVNSRAWPNG AVVADPMQPP PIAEEIDLLV FDLKTMREVR RALRAHRAYT PNDECFFIFL DVSRDFVASG AEDRHGYIWD RHYNICLARL RHEDVVNSVV FSPQEQELLL TASDDATIKA WRSPRTMRVL QAPRPRPRTF FSWLASQRR

Target Information

This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.