Thermo Fisher Scientific CD123 Polyclonal Antibody
CD123 폴리클로날 항체로 인간 IL3RA 단백질을 인식하며, IHC(P)에서 1:50~1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 비결합형 액상 형태. AML 연구 등에서 IL-3 수용체 신호 전달 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IL3RA. Recombinant protein control fragment (Product #RP-92264) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789263 |
Product Specific Information
Immunogen sequence:
PPITNLRMKA KAQQLTWDLN RNVTDIECVK DADYSMPAVN NSYCQFGAIS LCEVTNYTVR VANPPFSTWI LFPENSGKPW AGAENLTCWI HDVDFLSCSW AVGPGAPADV QYDLYLNVAN RRQQYECLHY KTDAQGTRIG CRFDDIS
Target Information
IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and forms a heterodimer with the common beta (βc or CDw131) subunit.
IL-3Ra transmits the signal of Interleukin-3, and its heterodimerization with IL-3Rb is required for receptor activation.
IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells, making them potential targets for therapeutic agents.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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