Thermo Fisher Scientific CaMKII gamma Polyclonal Antibody, FITC
FITC로 표지된 CaMKII gamma 폴리클로날 항체로, 인간, 마우스, 랫트 시료에 반응합니다. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합하며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되어 높은 특이성과 신뢰성을 제공합니다.
- 카탈로그번호
- CAMK32-FITC
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:100–1:250 |
| Dot Blot (DB) | 1:10,000 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 350–400 on human CaMKII gamma protein |
| Conjugate | FITC |
| Excitation/Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation. It is involved in dendritic spine and synapse formation, neuronal plasticity, and regulation of sarcoplasmic reticulum Ca(2+) transport in skeletal muscle. In neurons, it plays a structural role in actin cytoskeleton reorganization, essential for proper targeting of CaMK2A, which promotes dendritic spine formation and synaptic plasticity, enabling long-term potentiation and hippocampus-dependent learning. In skeletal muscle, it modulates Ca(2+) transport and release through phosphorylation of triadin and phospholamban.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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